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    Weidberg Lab

    Research Focus Teams: Aging, Rare Diseases

    Lab Team

    Dr. Hilla Weidberg
    Hilla Weidberg

    Assistant Professor

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    Mitochondrial protein quality control

    During import stress un-imported proteins stall in the mitochondrial import channels. One function of the mitoCPR is to alleviate this stress by extracting stalled proteins from the channels. We aim to elucidate the mechanisms by which proteins are recognized and extracted from the membrane during import stress.

    Mitochondria to nucleus signaling

    Communication between mitochondria and the nucleus is crucial for maintaining mitochondrial function and, consequently, for cell viability. We study the signaling route between these organelles during protein import stress. Our goal is to identify the mitochondrial signal that is sensed by cells to activate the mitoCPR.