Research Focus Teams
TBD
Research Interests
Arthritis/Osteo-Arthritis, Auto-Immune Diseases, Bone Tissue, Proteases, Protein structure and function
Departments
Biochemistry & Molecular Biology, Oral Biological & Medical Sciences
Bio
Dr. Dieter Brömme is a nationally and internationally recognized biochemist whose main research has been on cysteine proteases, protease inhibitors and the role of cathepsins in human diseases. He is a Canada Research Chair in Proteases and Disease. His research aims to better understand how proteases work, where and when they are produced in the body, how they destroy tissues and how they can be stopped from doing this. His particular interest is focused on a group of proteases called cathepsins, which play a critical role in musculoskeletal, respiratory and cardiovascular diseases.
Many proteases are considered as potential drug targets for a large variety of diseases. By improving the knowledge of how proteases work and finding novel drugs inhibiting proteases, Dr. Brömme's research could lead to new treatments for degenerative and inflammatory disorders.